Running a healthcare company of any kind can often be a very daunting task. There is so much involved in it, so much that you need to be aware of and keep in line, and it can often feel as though you are constantly pushing against backlogs, complaints and bureaucratic procedures when you just want to be able to care for your patients and clients. Most leaders and entrepreneurs in the world of healthcare find that it’s helpful to have an appropriate practice management system in place, and this is certainly something to consider.
But if you are looking for such a system, you might find yourself wondering which one to go for. There are, as you may have noticed already, loads out there, so you have a lot to choose from. In this post, we are going to take a look at some of the best practice management systems for healthcare companies in use in 2025. Any of these could serve you very well.
1. Acuitas 3
This might be the very best all-round healthcare software, and it’s certainly an incredibly helpful practice management system that seems to have all the perks that you would hope for, with very few of the common drawbacks that you tend to see. Acuitas 3 is actually made specifically for the optical industry, and part of its charm is that it is made by optometrists, for optometrists – so they really know what is needed. It helps eye specialists to manage everything in their practice – from booking appointments to managing stock control and dispensing, and so much more – and it does it all from within a powerful yet simple interface.
This is a fully cloud-based and highly accessible suite, and absolutely the go-to industry standard for optometrists and eye specialists everywhere.
Best For
- Designed for optics – this is purpose built for optical practices with the ability to support independents as well as global chains.
2. Athenahealth
You may have heard of Athenahealth, as it is genuinely one of the most popular and famous such practice management systems in the world. It is a legitimately all-in-one cloud-based program and as such, it tends to suit cloud-based practices. It is a leader in interoperability, with real-time claims tracking, integrated EHR, and lots of new telehealth features too. The billing tools are some of the most robust out there, and it plays really well with third-party systems, so you don’t have to only rely on this if you don’t want to.
It’s particularly good for appointment scheduling and medical billing, as well as helping to improve patient communication.
Best For
- Probably the real-time reporting which allows a much greater sense of control over the whole practice each and every day.
3. DrChrono
If you are running a smaller enterprise, you might find yourself looking to the likes of DrChrono. This system is built with iOS in mind, and it offers a really sleek and modern-feeling interface with a strong mobile EHR capability, as well as flexible medical billing tools. It’s a great one for anything up to midsize practices that want to have everything in one place, and has some really strong and lesser-seen key features such as an easy-to-use patient portal and customizable templates. It’s also known as one of the best software suites for billing.
Best For
- Mobile-first practices, and smaller teams that are still building up.
4. Kareo Clinical
Kareo Clinical is tailor-made for the smaller, independent practices, and as such is known to offer a genuinely straightforward and easy system to use for any professional who just wants to have everything in one place. That can mean that it is less powerful than some systems, owing to its lack of overcomplication. But on the whole, it’s an excellent option for practices that want to get up and running quickly, and it is proving very popular amongst newer and smaller practices in general – with good reason.
Best For
- Independent practices and smaller teams who just want a handy tool to make their day a little easier.
5. NextGen Healthcare
This has a really strong support for speciality workflows and also some of the most highly customizable interfaces in the healthcare world. That means that it is empowering, and that’s the overarching feeling that people tend to get when they are using this product. It’s really ideal for practices with some more unique documentation needs, and it’s an ONC-certified system that supports value-based care models, which is what makes it perfect for so many medical practices out there. It has some strong key features including good analytics and patient engagement tools too.
Best For
- Speciality practices and enterprise-level scalability.
7. AdvancedMD
The main thing you need to know about AdvancedMD is that it is highly modular. That means that you can use it as a growing practice to help scale up your operation easily and effortlessly, without having to worry about switching over to different suppliers halfway through your growth cycle. It offers advanced reporting, telemedicine, patient engagement features and so much more, and has a strong revenue cycle management process too, which is something that a lot of these software options really do lack. All in all, it’s a great choice for so many practices, and one that you are definitely going to want to consider.
Best For
- If you are running a multi-level practice, or your practice is growing fast, the modular nature of this system will serve you very well.
As you can see, there are a lot of practice management systems out there, and they vary widely in terms of what they are offering. If you are keen to get a system that works for you, take a look at those above, and consider what your specific needs might be. Chances are you will find what you need here, and if all else fails you can be sure to succeed with an all-round system as above. Anything to help you run your practice effectively and continue to offer great support to your clients.
